The Director Non-Clinical Due Diligence & External Evaluations provides scientific leadership for nonclinical due diligence supporting CSL’s in-licensing, acquisitions, and strategic collaborations. The role ensures integrated, objective, and decision-relevant evaluations of nonclinical pharmacology, PK/QSP, and toxicology data to identify development risks, data gaps, and mitigation strategies and to inform portfolio decisions. The incumbent will also act as nonclinical representative for selected Research programs and support oversight of nonclinical strategies and programs across all Therapeutic Areas.
Tasks
- Lead operational execution of nonclinical due diligence for assigned opportunities.
- Act as hands-on scientific integrator, translating expert input into clear risk narratives.
- Serve as subject-matter lead for nonclinical due diligence on individual deals.
- Lead end-to-end nonclinical due diligence for individual assets or transactions, from request through final governance readout.
- Integrate input from Toxicology, PK/QSP, Nonclinical Pharmacology, and external experts into a single, coherent scientific assessment.
- Identify FIH-enabling gaps, translational risks, and regulatory limitations, with clear mitigation proposals.
- Prepare high-quality due diligence reports, executive summaries, and risk tables for governance review.
- Act as nonclinical development scientific interface to Business Development and Therapeutic Area teams at the project level.
- Contribute to maintenance and continuous improvement of nonclinical due diligence frameworks and templates.
- Mentor junior contributors and matrix team members as appropriate.
- Escalate complex or high-impact issues to Head of Nonclinical Development.
- Chair the Nonclinical Development Review Committee.
Requirements
- Advanced degree (Ph.D., D.V.M., or equivalent) in toxicology, pharmacology, or a related field.
- Toxicology training, board certification preferred.
- Experience in nonclinical development (10+ years) with proven experience in due diligence or external innovation, ideally across various geographies.
- Strong understanding of FIH-enabling nonclinical requirements, particularly for biologics and complex modalities.
- Ability to communicate complex scientific risk clearly to non-expert stakeholders.
- Experience across multiple therapeutic areas and modalities is highly desirable.
- Proven ability to work effectively both independently or in a team setting, and to meet set goals by managing own timelines.
- Experience in working in cross-functional, multicultural and international teams.
- Excellent communication and analytical skills.
- Experience in analyzing and presenting research results to scientific and professional audiences.
- Strong planning and organizational skills.
- Ability to work successfully in a matrix organizational structure.
- Strong negotiation skills and ability to identify and engage internal and external expertise as needed.
- Good understanding of drug development process, strong knowledge of ICH/GLP.
- Fluent in English, oral and written.
- Onsite presence required 3 days per week.
- Role can be based in Zurich, Switzerland or Waltham, USA.
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