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The Biotechnology and Bioengineering group at the Department of Biosystems Science and Engineering (D-BSSE) of ETH Zurich in Basel invites exceptional candidates to apply for a PhD position in pioneering projects developing synthetic biology-inspired human therapies. The D-BSSE is an interdisciplinary research department uniting theoretical and experimental biology with advanced bioengineering, fostering collaborations with leaders in material science, physics, and chemistry to drive advances in systems biology, biotechnology, and synthetic biology. Located in Basel, Switzerland, at the heart of the BioValley, the D-BSSE offers a unique environment for high-impact translational research with access to academic and industrial expertise.

Tasks

  • Combine molecular engineering, cell programming, and chemical–biological interfacing to engineer human cells using synthetic gene circuits and biosensing platforms
  • Develop novel biosensing systems for real-time monitoring of cellular states
  • Create genetic architectures for precise therapeutic protein regulation
  • Translate research advances into programmable cellular implant prototypes
  • Collaborate closely with molecular biologists, bioengineers, and clinical researchers to accelerate translation into clinically relevant therapies

Requirements

  • Highly motivated and eager to bridge basic and translational research in cell biology and synthetic biology
  • Strong skills in molecular and cell biology techniques, including cultivation and engineering of primary human cells and mammalian cell lines
  • Experience with in vivo techniques is an asset
  • Completion of an accredited course in laboratory animal science (FELASA / LTK or equivalent) is an asset
  • Outstanding academic record
  • Enthusiastic about building a career in academia, industrial R&D, or biotechnology entrepreneurship

Benefits

  • Professional development support at ETH Zurich
  • Contribution to positive change in society
  • Commitment to a sustainable and climate-neutral university
  • Public transport season tickets and car sharing
  • Wide range of sports offered by the ASVZ
  • Childcare
  • Attractive pension benefits
  • Inclusive culture that promotes equality of opportunity and values diversity
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Über uns
Die ETH Zürich ist eine technisch-naturwissenschaftliche Hochschule des Bundes mit Sitz in Zürich. Wir betreiben Lehre, Forschung und Wissenstransfer in Bereichen wie Ingenieurwissenschaften, Naturwissenschaften, Architektur, Mathematik, Informatik, Management sowie Sozial- und Geisteswissenschaften. Unsere Ausbildung umfasst Bachelor-, Master-, Doktorats- und Weiterbildungsangebote und ist eng mit internationaler Spitzenforschung verbunden. Als Teil des ETH-Bereichs entwickeln wir wissenschaftliche Grundlagen, Technologien und Lösungen für Gesellschaft, Wirtschaft und globale Herausforderungen.
Das Team

The Biotechnology and Bioengineering group is led by Prof. Dr. Martin Fussenegger and collaborates closely with experts in molecular biology, bioengineering, and clinical research within an interdisciplinary environment.

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