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We are seeking a highly motivated postdoctoral researcher to join our group at the Department of Biology, ETH Zurich. The successful candidate will use state-of-the-art intravital microscopy to study macrophage biology and tissue repair in vivo. Our lab investigates how tissue-resident immune cells, particularly macrophages, contribute to tissue homeostasis and repair, with a focus on the mesothelium, serosal cavities, and the liver. Using intravital imaging, we track cell behavior and dynamics in real time within living tissue, linking cellular mechanisms to organ-level repair processes. The project has a strong translational angle, motivated by clinical challenges in abdominal surgery such as adhesion formation, and is conducted in close collaboration with clinicians to bridge basic mechanistic insight with surgical practice.

Tasks

  • Design and perform intravital microscopy experiments in mouse models
  • Extend intravital imaging approaches to additional organs
  • Investigate macrophage dynamics and/or serosal repair mechanisms
  • Analyze imaging data using quantitative and computational approaches
  • Perform spectral flow cytometry and standard bioinformatics analysis of single-cell and spatial transcriptomics data, correlating findings with imaging data
  • Present findings at lab meetings and international conferences
  • Contribute to manuscript preparation and grant writing
  • Co-supervise MSc/PhD students

Requirements

  • PhD in Immunology, Cell Biology, or a related field
  • Prior experience with rodent models required
  • An interest in tissue repair or regenerative biology is a plus
  • Hands-on experience with intravital/in vivo imaging is an advantage
  • Strong quantitative and image-analysis skills are an advantage
  • Solid R and/or Python skills, ideally paired with modern AI-assisted coding workflows (e.g., Claude Code), are a clear advantage
  • Track record of first-author publications
  • Excellent written and spoken English
  • Team-oriented mindset

Benefits

  • A newly established lab with cutting-edge fluorescent reporter models ready to be characterized
  • A vibrant, founder-like atmosphere as an early member of a young, growing team
  • Access to cutting-edge intravital imaging infrastructure
  • A lab at the forefront of AI adoption in research, with access to high-end computational resources and environments
  • Mentoring and career development support
  • Initial 1-year contract with annual renewal; funding for the position is secured for up to 4 years
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Über uns
Die ETH Zürich ist eine technisch-naturwissenschaftliche Hochschule des Bundes mit Sitz in Zürich. Wir betreiben Lehre, Forschung und Wissenstransfer in Bereichen wie Ingenieurwissenschaften, Naturwissenschaften, Architektur, Mathematik, Informatik, Management sowie Sozial- und Geisteswissenschaften. Unsere Ausbildung umfasst Bachelor-, Master-, Doktorats- und Weiterbildungsangebote und ist eng mit internationaler Spitzenforschung verbunden. Als Teil des ETH-Bereichs entwickeln wir wissenschaftliche Grundlagen, Technologien und Lösungen für Gesellschaft, Wirtschaft und globale Herausforderungen.
Das Team

The position is in a newly established lab at the Department of Biology (D-BIOL), ETH Zurich, offering a vibrant, founder-like atmosphere as an early member of a young, growing team and close collaboration with clinicians.

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