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Lead innovative research in respiratory discovery with a focus on COPD pathobiology and drug target identification. At Roche, you are valued for your unique qualities and encouraged to thrive both personally and professionally. Join a culture that embraces personal expression, open dialogue, and genuine connections, aiming to prevent, stop, and cure diseases while ensuring access to healthcare for generations to come.

Tasks

  • Utilise patient data and translational models to lead initiatives for understanding COPD pathobiology and identifying novel drug targets.
  • Generate therapeutic hypotheses that are experimentally testable, druggable, and clinically developable.
  • Direct, oversee, and interpret complex preclinical experimental studies for validation and characterisation of targets or therapeutic agents in COPD.
  • Bring targets into the early drug discovery pipeline and lead multidisciplinary teams up to clinical candidate generation.
  • Evaluate external opportunities and communicate findings to senior management.
  • Coach and mentor junior scientists and postdocs.

Requirements

  • PhD degree in Life Sciences (respiratory biology, cellular/molecular biology, pharmacology, immunology, or a closely related field).
  • 5 to 10 years of experience in the pharmaceutical industry.
  • Deep expertise in COPD disease biology, including chronic tissue remodelling, inflammation, and/or epithelial biology.
  • Significant scientific accomplishments and successful collaborations documented by publications in high-impact journals.
  • Strong strategic thinking capacity with the ability to balance multiple priorities in a fast-paced, matrixed organisation.
  • Good understanding of general pharmacological properties of therapeutic modalities such as small molecules and antibodies.
  • Effective communication of scientific data and concepts to colleagues, teams, and senior management.
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Über uns
Roche ist ein international tätiges Schweizer Pharma- und Diagnostikunternehmen mit Sitz in Basel und entwickelt, produziert und vertreibt Medikamente sowie diagnostische Lösungen. Das Unternehmen ist in den Bereichen Pharma und Diagnostik tätig und fokussiert sich auf Forschung und Innovation in verschiedenen Therapiegebieten wie Onkologie, Neurologie und Infektionskrankheiten. Roche ist weltweit aktiv und zählt zu den führenden Unternehmen im Gesundheitsbereich.
Das Team

As part of Roche's Pharmaceutical Research and Early Development organisation (pRED), you will join the Cardiovascular, Metabolism, Immunology (CMI) team located in Basel, Switzerland. The Immunology Department develops cutting-edge therapies for chronic inflammatory diseases, including novel treatment options for COPD. You will work in an international and multidisciplinary group of scientists and clinicians committed to delivering innovative solutions for COPD patients.

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