Join a dynamic research group focused on developing and applying human neural circuit measures to detect early stages of Alzheimer’s disease and related disorders. Work in a collaborative environment with strong academic and infrastructural links at the University Hospital for Geriatric Medicine Felix Platter (UAFP) and the University of Basel. You will be part of a translational setting, closely interacting with clinical services and benefiting from collaborations with leading international research teams.
Your tasks
- Design and lead human neurophysiology studies in ageing and neurodegenerative disease using EEG and/or MEG, cognitive tasks, and behavioural quantification.
- Develop sensitive circuit-level biomarkers of early disease for use across patient groups and over time.
- Integrate human circuit measures with fluid biomarkers from blood and CSF, relating biomarker dynamics to circuit signatures and behavioural changes.
- Contribute to interventional and experimental medicine studies, including pre-post designs and trial-adjacent add-on studies, to assess treatment response at the circuit level.
- Build cross-species links by aligning human circuit measures with mechanistic readouts from mouse models.
- Apply computational and statistical methods to analyze large-scale neurophysiological and behavioural datasets.
- Contribute to study design and interpretation across modalities, integrating neurophysiology with molecular and clinical phenotyping.
- Prepare manuscripts and grant applications, and present findings at national and international meetings.
What you bring
- PhD in Neuroscience, Cognitive Neuroscience, Biomedical Engineering, Physics, Computer Science, Mathematics, or related fields.
- Expertise in human neurophysiology and brain imaging data, with a strong track record in MEG and/or EEG research.
- Strong analytical and computational skills for large-scale data analysis (Python and/or MATLAB) and solid statistical reasoning.
- Experience designing and running cognitive and behavioural paradigms in humans, ideally with patient-facing research experience and awareness of ethical and regulatory requirements.
- Excellent written and verbal communication skills in English.
- Proven ability to drive independent projects and collaborate effectively in interdisciplinary teams.
- Interest in ageing, Alzheimer’s disease, and neurodegeneration, and motivation to build explicit cross-species translation.
- Advantageous but not required: Experience with rodent circuit methods (Neuropixels, in vivo imaging, or rodent behaviour) or motivation to gain this expertise through collaboration and training.
- Experience with computational modelling of behaviour and brain signals, multivariate prediction, or normative modelling.
- Experience with multimodal integration, including linking neurophysiology to molecular or clinical biomarkers.
What we offer
- Be part of a dynamic and collaborative research environment at UAFP and the University of Basel.
- Shape a cross-species circuit biomarker programme with direct clinical relevance.
- Interact closely with clinicians and clinical researchers.
- Access technology platforms and training opportunities through the Department of Biomedicine and the Department of Clinical Research.
- Competitive salaries and comprehensive social benefits.
- Family-friendly working conditions.
- Work in an inclusive environment that values diversity, equity, and respect for human values.
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Über uns
The University Hospital for Geriatric Medicine Felix Platter (UAFP) in Basel is dedicated to advancing research and clinical care in dementia and neurodegeneration. UAFP offers a collaborative and interdisciplinary environment with strong academic ties to the University of Basel, providing access to leading technology platforms, clinical services, and international research networks.