Join a multidisciplinary team advancing translational science and personalized cancer treatment. You will work with clinicians, cancer biologists, organoid and drug screening experts, bioinformaticians, and data scientists, using cutting-edge technologies like image-based drug screening and imaging mass cytometry to help inform clinical decisions for patients with advanced cancer.
Your tasks
- Drive the development of organ-specific heterotypic 3D co-culture models using patient-derived tumor material and optimize media compositions.
- Establish and scale miniaturized co-culture platforms in 384-well formats for automated high-throughput drug screening workflows.
- Design and execute comparative drug screening assays to evaluate therapeutic responses.
- Develop and apply automation workflows, including liquid handling technologies, for precise and reproducible cell seeding.
- Work closely with organoid specialists and data scientists in an interdisciplinary environment.
- Ensure clear documentation of experimental procedures and support translating methods toward clinically relevant, scalable high-throughput applications.
What you bring
- PhD degree or equivalent expertise in biomedical/tissue engineering, biology, biotechnology, or a related field.
- Hands-on experience with complex 3D culture systems and their use in cancer research.
- Strong knowledge of cancer biology and tumor microenvironment dynamics.
- Practical experience with imaging techniques and immunofluorescence.
- Strong organizational skills and a clear, pragmatic mindset.
- Highly motivated, creative, team-oriented, and collaborative.
- Excellent spoken and written English communication skills.
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Über uns
The Department of Biomedicine is a joint venture of the University of Basel and the University Hospitals Basel, bringing together over 67 research groups and more than 800 employees. Located in the heart of Basel, our collaborative and international environment fosters innovation, excellence, and impactful research in health and disease.
Das Team
You will join the Tumor Heterogeneity Metastasis and Resistance team led by Prof. Mohamed Bentires-Alj, working in a dynamic, interdisciplinary group at the interface of clinical research, biomedical imaging, and personalized oncology.