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The University of Zurich, Switzerland's largest university, offers a range of attractive positions in various subject areas and professional fields. With around 10,000 employees and currently 12 professional apprenticeship streams, the University provides an inspiring working environment focused on cutting-edge research and top-class education.
Tasks
- Operate and maintain the mass spectrometry infrastructure, including Orbitrap Astral instruments and supporting LC systems, ensuring consistently high performance.
- Coordinate, prepare, and process biological samples for stable isotope tracing, metabolomics, epitranscriptomics, and other MS-omics analyses, including low-input and single-cell samples.
- Support the implementation of automated sample preparation pipelines to increase throughput and improve reproducibility.
- Provide hands-on guidance and training to students and postdocs in the use of the instruments.
- Actively contribute to the development and optimization of LC-MS methods for metabolite quantification, isotope enrichment, lipid profiling, and modified nucleotides.
- Carry out routine instrument calibration, troubleshooting, and preventive maintenance independently.
- Support data acquisition as well as initial QC and processing pipelines.
- Perform MS data processing and analysis across applications and collaborative projects, ensuring high data quality and consistency.
- Manage MS data across projects to ensure traceability, organization, and reproducibility.
- Help manage consumables, sample logistics, and platform documentation.
Requirements
- MSc or PhD in analytical chemistry, biochemistry, or a related field.
- Solid practical experience with LC-MS/MS, ideally on Orbitrap-based instruments.
- Background in stable isotope tracing and/or metabolomics in a biological setting is strongly preferred.
- Interest in or experience with laboratory automation, such as liquid handling, automated sample preparation, or scripted workflows.
- Curiosity about emerging technologies, particularly single-cell mass spectrometry, is a genuine plus.
- Methodical, detail-oriented, and comfortable troubleshooting complex instrument issues.
- Able to work independently and communicate clearly with researchers at all levels.
- Experience in a core facility, CRO, or research lab environment is valued.
- English required; German is a plus.
Benefits
- Flexible working models, including part-time positions, mobile working, and job-sharing.
- Childcare at the kihz foundation of UZH and ETH.
- Wide range of continuing education courses offered by UZH and the Canton of Zurich.
- Language Center run jointly with ETH Zurich.
- Food and drinks at reduced prices in UZH cafeterias.
- Lunch-Check-card with UZH contribution.
- Special conditions on the Academic Sports Association ASVZ.
- Free seasonal flu vaccinations.
- Rest and relaxation at the quiet room in the university tower.
- Discounts on carsharing, vehicle rental, parking space, hardware, software, and mobile phone subscriptions.
- Employment according to UZH policies.
- Support for people from outside Switzerland.
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Über uns
Die Universität Zürich ist eine öffentliche Universität des Kantons Zürich und bietet Lehre, Forschung und Weiterbildung in einem breiten Spektrum wissenschaftlicher Disziplinen an. Sie umfasst sieben Fakultäten und verbindet akademische Ausbildung mit Grundlagenforschung, angewandter Forschung, Nachwuchsförderung und Wissenstransfer. Die UZH arbeitet mit nationalen und internationalen Hochschulen, Forschungsinstitutionen, Spitälern, Unternehmen und öffentlichen Stellen zusammen und leistet Beiträge in Bereichen wie Medizin, Naturwissenschaften, Wirtschaft, Recht, Gesellschaft, Geisteswissenschaften und Theologie.